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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef02a89e2da72edf86a707c18c760483110cf6002e3ed16207d0d0e0688718c' 
  AND token = 'Eiq3d1s3e3Z71nCd/fUOgNsnT0Z3Zlkcgf6xDbOCvNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}