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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aea002283e8d6c655b18bbcca349a8316e81f3b70fb040661f29511e21aa73a' 
  AND token = 'R7qkiD1CiBozBs24nwbUqJmWikVi/2hU842CVzpNaSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}