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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c4fb6e0f050d359f5cc71a2f220927748cc9a5657d880a0d0e043f69064563' 
  AND token = 'evc5KYTDnOJxYtiJALlmHwF+0dZ21g0WNbTWHwlH+qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}