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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b47b3149bf9464f027937da32bc9681844451d47c55023a5d760d4138ea9d88' 
  AND token = '5tgWAAztzMr3wE/TEORRX7I61nKDE8TKHSDGl/TdoZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}