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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291facca47e175131cdc96cbc07468bbac8fc644c0f9a72361f83f5a333a18ea' 
  AND token = 'OksVLU4VaHx1FY6Q0/Q1czrr4Z4oUU+5WD5Kj231XMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}