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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b7d8cf42588e022c959b91b5d391bdb78b686c121903e07441137d7dee44f4' 
  AND token = 'F3JMagAM+dJmbGrmUM5U3fpw62PIwhF1DImbPmugDjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}