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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '283e536d407643a4cf6d6e1fe25ff769c1cd193693ede903d04ab9239ce81801' 
  AND token = 'jw9eQQ0tgAlTF/8LGeOTqOxj/ChjLtxVMOfWpq0wlUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}