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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5fd42ad75f85b2aa0216760840d85c259395535d6fec547f32cb634cd6224c' 
  AND token = 'j4tMPOFrA0DGyLXpxPVkud63oCStR4UC/2Dcv6cWXW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}