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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800b1c653be4a6e0a2036aed45b4f718dd237cce913de2c88b619ecc3abb81b9' 
  AND token = 'cy3ck7Jyl/IKsgQUSj3z7jBwIZSpliJRIMG1SqaWtpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}