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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b46f504bd0c9aeea272530e28e7903878d208fccfb5c006af0f68044cc2b0ab' 
  AND token = '+Lxb01NGj0yawyk5k+yyWDLQ8Y+k1JUrenb9SmD/+nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}