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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d16a40325434d6a1f9f76e58bb86d22b4e8f562227c3a4c7ca1fb390b16ee86' 
  AND token = 'UGGjbMeLdRrJQ+nHrbQ/KPBy9UdBeJIGPWaIQEhWDoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}