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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12fee6b11bf13fe0aa14845ae0832be0d74461a4f6a37805269c5e96f1648cf' 
  AND token = 'DnTpNdHD+e/s2NBqA5uBd+zk8mp5DBugM3FuulclbUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}