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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b9ed0f536a726259d5c4b2f453baf69022a4374554e169606f1315b4f94bdb' 
  AND token = 'Qldp+XlX1vqy3o1VRjwePUcar+MajRJq+kRXK77WeT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}