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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51081226f84603372dd86c1f7a26a915bd1adcfec70fb1eb00fd53bea5920b43' 
  AND token = 'k+Lr7SJT1dFE0zuz8/U6pgB0sFaEUDOn3jOVWueEhm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}