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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462043e5a20b29027171ae42d04b4397aa605854f9136a91283eca49645cb42a' 
  AND token = 'Zy1fRk/mjrSsL6Ip+iQN/RTpyRjexdnBfTHM0JmejMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}