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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0c6691d5e1e1399ec175b7e8c2cbc7588e7da32d73ea6e22657642405b9727' 
  AND token = '8GVRQJmmGNb4ZTkVjWETjbMjKneWvsWkC29oluGwFeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}