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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77fa165bca1079fc057c7220dfef6a05d25f5d728caae64df8a1883256222d6' 
  AND token = '/men3l5fv7RnF0ZmmzfieL5X4+y1kMRgKWZnvb9axMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}