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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c4880410585bf1619d8ac28c386f5cefe3af6b24ddccaae6784013aab11bfa' 
  AND token = 'xkZVCGDzzvm/Ndup79L+VKBDU/X4xHGC0Dft92oAxe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}