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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a0cc39c4cd12f00d84b8ff48b49efdd7f5b9ab489cbe7332956135ab46061d' 
  AND token = 'ESO2bgUAYK/lDvfnTaO9E+G/CfA44PBxtcf/VE3xTUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}