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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40836d100de49b6c071484e39f1bbbf48fd399a44e3f465a2f43069563ca105f' 
  AND token = 'xidYMgHH2U1O8prKl3r+ytaJI2JJEkOuihAiFFh4VAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}