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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77868a02d39f6bf48d4f13a0718396de273080b4450dcf9b8672e71ca23642ee' 
  AND token = 'OFkvC5ycjrso+c6om2OpBhX9+SGONekBIxFse9r4Bec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}