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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad0ff3bece809a4c8e18fe4996a7d3cda2e940b4c21fb789b3045cff07f81f3' 
  AND token = 'kxBKW14ZSTiS0/Kjp7VonIaGzhPAbWSzCnHxd2a9Z9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}