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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64a660a4cd6b6772210f43c1272c8d250e1b7cf11246d8bfae3920bd24b3ae1' 
  AND token = 'Z5EAkL5DKlJVkyTDjg0gvU+AxSGACulIv+JtN6DG9b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}