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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8296770dc5330a0cb2a252d73bb9c8ca39c855ef0351ead3c0845ead25dfa3' 
  AND token = '1sFrsqZTq6pyDZbg6tEM/uzl/c1+PMUu0gM8XUeJ4WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}