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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ef383258947f3991a45d20a6756c1ca39139d32c58ff4ae0e8ec4315bd83e6' 
  AND token = 'W5UxbFQfc0jHdWE2eHDxx6vyVFpjdAo5CIkVFpaJVdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}