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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495c3f3e8514273b29f1b3c330d123ca4187bfcb0ae955396693ab3bf29f6ccd' 
  AND token = '0U7ii+r0Tw1F74YuLa8tUlMeM3I70MHLCerB2W6Izyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}