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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcbd2737b8aa8d2e38cc432e4553a717f1ba1a60301523f43dc55a710081ad71' 
  AND token = 'OOWaOeq1TXoF0zUsl3pAZ4AW2S2PoOud3vQs4XPyXN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}