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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a7486da5cc0c981e6350e36995b8663652238c00af960d70a711001a7b507f' 
  AND token = 'm4gsfqmr1tNoAI9o2JUEpO7b7vMIy8VpSnDwtzXKne0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}