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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e013e46b237245b9a545ff6ddefa382506e98ae91f0649f60e314a35bf485168' 
  AND token = '3bkMOeWe78jNFKri+zqvKr6+Y1LlxyLz4+Zs15MC+Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}