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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95095b502f038fb126067a00f47bd0ee443297a2fd01003c949184493868fe51' 
  AND token = 'KyuwA/hpEK+MOV6BbaK4tYUUF7Wy+QI+r31jTUhxTEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}