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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301ad88e5309b1a768b38807f8ee246df73561b45539e7f9d6ca3adf88714337' 
  AND token = 'L0y7P/aSd3xGtcdJ9UcdaYstYyvox619pyk3OArU5xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}