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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bed8ae77790720fc59a6323e2d0f60cedc0bc83f069e413e710e00a155bb18e' 
  AND token = 'XJihh+ZnA9fqOFvWjd4y/+WdJ/s3mUF2+YZ/fkpNxkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}