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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2ab072a5a2131d436f1c01dfea37087f8cb739c99eb8f11e41b3311d54a083' 
  AND token = 'WIrtNpuhWoXnMRGGAJevyO12+41tjyyhd3pf4Z7lu7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}