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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc1df47af9bca7f470b9b37914c1b3a6acfa283ac5d20a110596d02040c2831' 
  AND token = 'vc+1UsRobdMh18GyTbxJy4sdMn3imYSzSfdzqDTIim0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}