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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9408caad59fa74581db75bbbfc211a4e074a269cff5cbfbf85e1a17f2fda9b78' 
  AND token = 'aWXLE7+0h2fLeqt3BrAsoCXMq43raIGkh4eWgBs1BHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}