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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4ebd764d77fa053c8cfa5450fcd4107094f9cb1f1a3fdfa1f484c7198dba2b' 
  AND token = 'DLQ/JSMkRMQvMIIeazz4VjIgVsHeIFTLLVKm+aF/GdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}