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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ddf0c27ef6f65523ae79801f6065fd38a275d5fc44855898495e9dcf56a964' 
  AND token = 'F+3WlfMK5upvLVRTKy65wblCl2gxjB+dQAut/D9JQHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}