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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b0ab72f26dd70728f9344b7c684bb17881fe294f9c42e1966f1849b85cc5090' 
  AND token = 'W7Bt6OJuYTX57cZFr7EwdPOPHYJKslI4y7Ytn6TG4B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}