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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8386e7a900027f3d01dadd8af68cdfaa56883e7a219d081cdba4a38cfc1db9ff' 
  AND token = 'MLiFZ0dsSLn5y9pMlLsNDFaCWaB4xd/S1W2mUNYcTNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}