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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf376743171da149a5fb527c8d5108d7116cbf0b90fdb7d8bbf81da5a5aff97' 
  AND token = 't7asWXsJnx6J8JN1aH7a+Y2rVmSWK94IEeJfQSmS3Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}