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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2a0c81578581d2db6a3005750a444e34293313a7654c0faaa9ec8157167f1e' 
  AND token = '6FGn4ynfiq+6TV/sRlgtaI9f7hB+u9qLqMEWPtOO9ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}