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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effca9b740aff207eeac1b3515e6ba9c6193f1ce9565851922f1d6d5c20a14f6' 
  AND token = 'fza65gOIptqSc3f3Qb/lBrcgmd+HywYLm77rl6meSv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}