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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8f543cec2fee72655aaf56c65b93381e3fd2d260d599d8149442243c9b5bac' 
  AND token = 'CnAxrj0PiLI6sUAGI6N6ZNbW6tAaQ4a7XXAeIQQ6Z6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}