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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6839bfd8f949c8c66514f45568ee5c7ddf3d3d6660e9f649453539c479734af' 
  AND token = '+eDKECuY+2VdgBDsM0JLm2S+gf5jiVmbpN6zy5rXnj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}