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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11547a0d4731aa67f58a13d8d0134e586ffe61bcdc980976edee7b667b2fc322' 
  AND token = 'IcLkng0kzmCbn//D5LTzer5g0tZTaBtV1AjtEobQK+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}