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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7916a96dd95ebb811c2d49e18d0f0d036f837d5d8cf95726bf5700b3178cec' 
  AND token = 'mISz5KJnrPfMKpm7GPdL8oHlHdshk4PMAjo+L55WfuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}