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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fce14fff29b4a411588ee481fc672cfe55b6daea582cd3fd87ca4e84483f21c' 
  AND token = 'SYI4x9W39LgHNMWWx4qo26QVhkh7uPKbjtPGPY9Jw4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}