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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bfdeb368dd12df8016935a6a1b9762d2ff92160aeb5d55626436675d524691' 
  AND token = 'pkzTQ7MSz81ypRhptkorWRXt+U2EiAxAMrnnTzaD7eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}