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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3b373825cde66d8b2323c1caaa99ea2187dea834563d7dd38bca478e2a2f4c' 
  AND token = 'HMopdMqiv3OWUsNXb4pLT9jCi1rGZF/wJ0Hvh+h+6r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}