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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f23882fe200951d88a82d9e632d90271e4b83cf59465cf2b239140e74a9bdde' 
  AND token = 'd/p8GC5ojeop2FhlU1Rx5aBtQgOfRw4fPI5LcAzleAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}